240 Medicines

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MedicineYr6Indication(s)MechanismOther Example(s)Relevant Scenario(s)
0.9% sodium chloridedehydrationintravenous fluid[Acute presentation of diabetes mellitus], [Infectious disease outbreak], [Postoperative care], [Postoperative complications]
5% dextrosehypoglycaemiaintravenous fluid[Acute presentation of diabetes mellitus], [Infectious disease outbreak], [Postoperative care], [Postoperative complications]
abciximabcoronary angioplastyglycoprotein IIb/IIIa receptor antagonist[Acute chest pain], [Epistaxis]
acarbosetype 2 diabetesalpha glucosidase inhibitor[Type 2 diabetes mellitus]
acitretinpsoriasisvitamin A analogue[Rash on extensor surfaces and joint pains]
acyclovirHerpes virus infectionnucleoside analogue DNA inhibitor (prodrug) (Class: antiviral)[Dysuria]
adalimumabrheumatoid arthritistumour necrosis factor inhibitor[Rash on extensor surfaces and joint pains]
adrenalinecardiac arrest, shock, acute allergic reactionsympathomimetic[Child with respiratory distress], [Compromised airway], [Out of hospital cardiac arrest], [Heart failure]
alendronateosteoporosisosteoclast inhibitor (Class: bisphosphonate)
allopurinolgoutxanthine oxidase inhibitor[Gout / acute pain and swelling of knee]
aluminum hydroxidepeptic ulcer diseaseantacid[Chronic upper abdominal symptoms]
amiloridehypertensiondistal tubule sodium reabsorption inhibitor (Class: diuretic)
amiodaronearrhythmiaspotassium channel blocker[Arrhythmias], [Out of hospital cardiac arrest]
amoxicillin and clavulanic acidbacterial infectiontranspeptidase inhibitor & beta-lactamase inhibitor (Class: antibacterial: beta lactam - penicillin)[Pneumonia]
amphetaminedrugs of abuseadrenergic neurotransmitter releaser[Alcohol and drug dependence disorders]
amphotericinfungal infectionsergosterol membrane channel opener (Class: antifungal)
anastrazolebreast canceraromatase inhibitor
artemisininmalariagenerates oxygen free radicals from heme (Class: antiprotozoal)
aspirinischaemic heart disease, cerebrovascular disease, peripheral vascular disease (antiplatelet), paincyclooxygenase inhibitor[Accidental overdose], [Acute chest pain], [Acutely painful limb], [Chronic limb pain], [Epistaxis], [Pre-admission and surgical risk assessment], [Preoperative assessment and management], [Risk assessment in early pregnancy], [Self-harm]
atazanavirHIV infectionprotease inhibitor (Class: antiviral)
atenololhypertension, ischaemic heart disease, arrhythmiasbeta-1 adrenoceptor antagonistbisoprolol, carvedilol
atropinebradycardia, treatment of cholinesterase inhibitor overdose, pupil dilationmuscarinic cholinergic receptor antagonist[Infant with an altered light reflex]
azathioprineinflammatory bowel disease, inflammatory arthritispurine synthesis inhibitor (prodrug)[Itching child]
beclomethasoneasthma, chronic obstructive pulmonary diseaseanti-inflammatory corticosteroid[Chronic shortness of breath], [Adult eczema], [Headache, morning stiffness and shoulder pain], [Hip fracture], [Itching child], [Sudden loss of vision and headache], [Sudden onset shortness of breath]
bendrofluazidehypertensiondistal tubule sodium reabsorption inhibitor (Class: diuretic: thiazide)
benserazideused with levodopa (Parkinson's disease)DOPA-decarboxylase inhibitor
benzoylperoxideacneacne treatments
benztropinedystonia, Parkinson's diseasemuscarinic cholinergic receptor antagonist/histamine (H1) receptor antagonist
benzylpenicillinbacterial infection, prophylaxis against group B streptococcal disease in labourtranspeptidase inhibitor (Class: antibacterial: beta lactam - penicillin)benzathine penicillin, flucloxacillin, amoxicillin[Child with respiratory distress], [Child with sore joints]
bezafibratedyslipidemiafibrate[Acutely painful limb]
branconstipation (irritable bowel syndrome)bulk laxative
budesonideasthma, chronic obstructive pulmonary diseaseanti-inflammatory corticosteroid[Child with respiratory distress], [Chronic shortness of breath], [Adult eczema], [Headache, morning stiffness and shoulder pain], [Hip fracture], [Itching child], [Sudden loss of vision and headache], [Sudden onset shortness of breath]
cabergolinehyperprolactinemiadopamine receptor agonistbromocriptine
calcipotriolpsoriasisvitamin D derivative[Rash on extensor surfaces and joint pains]
calcium hydroxidepeptic ulcer diseaseantacid[Chronic upper abdominal symptoms]
cannabisdrugs of abusecannabinoid receptor agonist[Alcohol and drug dependence disorders]
carbamazepineepilepsysodium channel blocker[Bipolar affective disorder], [Chronic illness in paediatrics], [Unexplained loss of consciousness]
carbidopaused with levodopa (Parkinson's disease)DOPA-decarboxylase inhibitor
carbimazolehyperthyroidismthyroid peroxidase inhibitor[Hyperthyroidism], [Hypothyroidism]
carboprostpost partum haemorrhageprostaglandin analogue
caspofunginfungal infectionbeta(1,3)-D-glucan synthase inhibitor (Class: antifungal)
cephazolinbacterial infectiontranspeptidase inhibitor (Class: antibacterial: beta-lactam - cephalosporin)cefuroxime, ceftriaxone[Child with red swelling around one eye], [Child with respiratory distress]
cetirizineallergyhistamine (H1) receptor antagonist
chloramphenicolbacterial infectionprevents 50S transpeptidation on 50S ribosome subunit (Class: antibacterial)[Hearing loss]
chloroquinemalariaheme breakdown inhibitor (Class: antiprotozoal)quinine
chlorpheniramineallergyhistamine (H1) receptor antagonist
cholecalciferolosteoporosisvitamin D[6 week check], [Child with abnormal gait], [Infant or child with pallor], [Rash on extensor surfaces and joint pains]
cholestyraminedyslipidemiaion-exchange resin[Acutely painful limb]
ciclosporinorgan transplant immunosuppressioncalcineurin inhibitor (Class: immunosuppressant)[Itching child], [Rash on extensor surfaces and joint pains]
cilazaprilhypertension, heart failureangiotensin converting enzyme inhibitor[Heart failure]
cimetidinepeptic ulcer diseasehistamine (H2) receptor antagonist
ciprofloxacininfectiongyrase inhibitor (Class: antibacterial: fluoroquinolone)norfloxacin
cisplatincancerformation of DNA crosslinks (Class: chemotherapy)
clomethiazolesedationpositive allosteric modulator of GABA-A receptor
clomipheneinfertilityselective estrogen receptor modulator (Class: ovulation induction agent)[Infertility]
clonidinehypertensionalpha-2 adrenoceptor agonist
clopidogrelischaemic heart disease, cerebrovascular disease, peripheral vascular diseaseADP receptor (P2Y12) inhibitor[Acute chest pain], [Acutely painful limb], [Chronic limb pain], [Epistaxis], [Pre-admission and surgical risk assessment], [Preoperative assessment and management]
clozapinepsychosisdopamine, serotonin, histamine (H1) and adrenergic antagonist[Acute psychosis]
coal tarpsoriasisskin cell growth modulator[Rash on extensor surfaces and joint pains]
codeinediarrhoea, analgesia, drugs of abusemu-opiate agonist (prodrug)[Dislocated joint]
colchicinegoutmicrotubule inhibitor
colloidsdehydrationextracellular volume expander
cromoglicateasthmamast cell stabiliser[Child with respiratory distress]
cyclizinenausea and vomitinghistamine (H1) receptor antagonist
cyclophosphamidecancer, autoimmune diseasenitrogen mustard alkylating agentchlorambucil, melphalan[Lymphadenopathy and splenomegaly]
cyproterone acetateprostate disease, androgen excess syndromesandrogen receptor antagonist
dabigatrantreatment and prevention of venous thromboembolism, atrial fibrillationthrombin inhibitorrivaroxaban[Unexplained loss of consciousness]
desferrioxaminepoisoning, iron overload disordersiron chelating agent
desmopressinsynthetic vasopressin, promotes release of von Willebrand factor/VIIIanti-diuretic hormone receptor agonist, promotes release of von Willebrand factor/VIII[Child with disorder of elimination], [Diabetes insipidus]
dexamethasoneinflammatory disease, steroid deficiency, foetal lung maturationanti-inflammatory corticosteroidmethylprednisolone[Adrenal crisis], [Obesity], [Secondary hypertension], [Adult eczema], [Headache, morning stiffness and shoulder pain], [Hip fracture], [Itching child], [Sudden loss of vision and headache], [Sudden onset shortness of breath]
diazepamsedationbenzodiazepine receptor agonist
diclofenacpain, inflammationcyclooxygenase inhibitor (Class: non-steroidal anti-inflammatory drug)
digoxinarrhythmias, heart failuresodium potassium ATPase inhibitor[Accidental overdose], [Heart failure]
diltiazemarrhythmias, ischaemic heart diseasecalcium channel blocker (Class: nondihydropyridine calcium channel blocker)
docusate sodiumconstipation (irritable bowel syndrome)surfactant[Late pregnancy complications]
domperidoneprokinetic agent, nausea and vomitingdopamine receptor antagonist[Bowel obstruction], [Penetrating chest trauma], [Sudden onset severe headache]
donepezilAlzheimer's diseaseacetyl cholinesterase inhibitor
doxazosinhypertension, benign prostatic hypertrophyalpha-1 adrenoceptor antagonist
doxorubicinmalignancyDNA intercalation (Class: chemotherapy: anthracycline)daunorubicin
doxycyclinebacterial infectiontetracycline - blocks tRNA access to 30S ribosome subunit (Class: antibacterial)[Pneumonia]
efavirenzHIV infectionnon-nucleoside reverse transcriptase inhibitor (Class: antiviral)
eformoterolasthmabeta-2 adrenoceptor agonist[Chronic shortness of breath], [Sudden onset shortness of breath]
emulsifying ointmenteczema, dermatitisemollient[Itching child]
epoetin (recombinant human erythropoietin)anaemia (mainly renal and related to cancer chemotherapy)haematopoietic growth factor
ergometrinepost partum haemorrhageuterine muscle contraction stimulant
erythromycinbacterial infectionprevents transpeptidation on 50S ribosome subunit (Class: antibacterial: macrolide)clarithromycin, clindamycin, azithromycin, roxythromycin[Child with respiratory distress], [Chronic bowel motility problems], [Pneumonia]
etanerceptinflammatory arthritistumour necrosis factor inhibitor[Rash on extensor surfaces and joint pains]
ethambutoltuberculosisarabinosyltransferase inhibitor (Class: antibacterial)[Haemoptysis and abnormal chest X-ray]
ethanoltreatment of methanol overdosepositive allosteric modulator of GABA-A receptor[Alcohol and drug dependence disorders], [Chronic liver disease]
ethinylestradiol/levonorgestrelcontraceptionoestrogen analogue/progesterone receptor agonist (Class: combined oral contraceptive)
ethosuximideepilepsyT type calcium channel blocker[Unexplained loss of consciousness]
etoposidecancerinhibition of topoisomerase leading to DNA strand breakage (Class: chemotherapy)
felodipinehypertensioncalcium channel blocker (Class: dihydropyridine)amlodipine
fexofenadineallergyhistamine (H1) receptor antagonist
filgrastim (recombinant human granulocyte colony-stimulating factor)neutropeniahaematopoietic growth factorepoetin
finasteridebenign prostatic hypertrophy, prostate cancer, androgenic alopecia, androgen excess syndromes5-alpha-reductase inhibitor[Elevation of prostate-specific antigen]
fluconazolefungal infectionsergosterol synthesis inhibitor (Class: antifungal: triazole)miconazole
fludarabinehaematological malignancypurine analog DNA synthesis inhibitor (Class: chemotherapy)cytosine arabinoside[Lymphadenopathy and splenomegaly]
fludrocortisoneaddison's diseasemineralocorticoid receptor agonist[Adrenal crisis]
flumazenilbenzodiazepine overdosebenzodiazepine receptor antagonist[Anxiety disorder], [Delirium / dementia], [Preoperative assessment and management], [Unexplained loss of consciousness]
fluoxetinedepression, menopausal symptomsselective serotonin reuptake inhibitorparoxetine, citalopram[Major depressive episode]
fluticasoneasthmaanti-inflammatory corticosteroid[Child with respiratory distress], [Chronic shortness of breath], [Adult eczema], [Headache, morning stiffness and shoulder pain], [Hip fracture], [Itching child], [Sudden loss of vision and headache], [Sudden onset shortness of breath]
folic acidfolate deficiency, pregnancyfolic acid supplementation[Child with abnormal gait], [Gynaecological abdominal pain], [Risk assessment in early pregnancy]
frusemidehypertension, heart failureloop of Henle sodium reabsorption inhibitor (Class: loop diuretic)
gabapentinepilepsy, analgesiaGABA analogue[Unexplained loss of consciousness]
gemfibrozildyslipidemiaperoxisome proliferator-activated receptor alpha agonist
gentamicinbacterial infectionribosomal protein synthesis inhibitor (Class: antibacterial: aminoglycoside)amikacin[Hearing loss]
glipizidetype 2 diabetespancreatic beta cell stimulant (Class: sulphonylurea)gliclazide
glyceryl trinitrateischaemic heart diseasenitric oxide prodrug[Acute chest pain], [Perianal pathology], [Stable angina]
goserelinprostate disease, infertilitygonadotropin releasing hormone superagonist
haloperidolpsychosisdopamine receptor antagonist[Acute psychosis], [Agitated and combative patient]
heparin-low molecular weightprophylaxis/treatment of venous thromboembolismantithrombotic agentrivaroxaban
heparin-unfractionatedprophylaxis/treatment of venous thromboembolism, acute peripheral arterial occlusionantithrombotic agentrivaroxaban
hydrocortisoneinflammatory disease, steroid deficiency, topical: eczema, dermatitiscorticosteroid receptor agonistmethylprednisolone[Adrenal crisis], [Panhypopituitarism]
hydroxycobalaminvitamin B12 replacementvitamin B12 deficiency
hydroxyureamyeloproliferative neoplasmsneoplasmsinhibits ribonucleotide reductase (Class: chemotherapy)
hypromellosedry eyeswater retaining celluloid
ibuprofenpain, inflammationcyclooxygenase inhibitor (Class: non-steroidal anti-inflammatory drug)
imatinibchronic myeloid leukaemia, gastrointestinal stromal tumoursoccupies active tyrosine kinase site in abl, c-kit and PDGF-R[Polycythaemia]
infliximabinflammatory bowel disease, inflammatory arthritistumour necrosis factor inhibitor[Rash on extensor surfaces and joint pains]
insulindiabetesinsulin replacement[Acute presentation of diabetes mellitus], [Diabetes in pregnancy], [Preoperative assessment and management], [Type 1 diabetes mellitus], [Type 2 diabetes mellitus]
interferoncancer, hepatitis B & C, multiple sclerosisantiproliferative, pro-apoptotic, anti-angiogenic, immune modulation (Class: immunosuppressant)thalidomide, lenalidomide
intravenous immunoglobulinimmune deficiency, autoimmune diseaseimmunoglobulin replacement, regulation of immune response
iodinepregnancydietary supplement[Fetal health], [Gynaecological abdominal pain], [Hyperthyroidism], [Hypothyroidism], [Infertility], [Pregnancy diagnosis], [Gradual deterioration in visual acuity over time]
ipratropiumasthma, chronic obstructive pulmonary diseasemuscarinic cholinergic receptor antagonist[Child with respiratory distress], [Chronic shortness of breath], [Sudden onset shortness of breath]
ipratropium+salbutamolasthma, chronic obstructive pulmonary diseasecompound bronchodilator
ironiron deficiencyhaematinic; mineral[6 week check], [Anaemia], [Chronic bowel motility problems], [Chronic upper abdominal symptoms], [Haemochromatosis], [Heavy menstrual periods], [Infant or child with pallor], [Overdose in a child or adolescent], [Upper gastrointestinal bleeding]
isoniazidtuberculosismycolic acid synthesis inhibitor (prodrug) (Class: antibacterial)[Haemoptysis and abnormal chest X-ray]
isosorbide dinitrateischaemic heart diseasenitric oxide prodrug
isotretinoinacnevitamin A analogue
ispaghula huskconstipationwater retaining bulk expander
labetalolhypertensionbeta-1 adrenoceptor antagonist
lactuloseconstipationosmotic laxative[Chronic bowel motility problems]
lamotrigineepilepsy, bipolar disorderglutamate release sodium channel blocker[Bipolar affective disorder], [Chronic illness in paediatrics], [Unexplained loss of consciousness]
latanoprostglaucomaprostaglandin F2alpha analogue
levodopaParkinson's diseasedopamine receptor agonist (prodrug)
levodopa+benserazideParkinson's diseasedopamine receptor agonist (prodrug) and DOPA-decarboxylase inhibitor
levodopa+carbidopaParkinson's diseasedopamine receptor agonist (prodrug) and DOPA-decarboxylase inhibitor
lignocainepain, arrhythmiassodium channel blocker[Arrhythmias]
linezolidbacterial infectionoxazolidinone - prevents initiation of protein synthesis at 50S ribosome subunit (Class: antibacterial: oxazolidinone)
lithiumbipolar disordersodium analogue[Bipolar affective disorder], [Self-harm]
loperamidediarrhoeamu-opioid receptor agonist[Chronic bowel motility problems]
lorazepamsedationbenzodiazepine receptor agonist[Altered level of consciousness in a child]
losartanhypertensionangiotensin II receptor antagonist[Heart failure], [Secondary hypertension], [Sudden onset severe headache]
lysergic acid diethylamidedrugs of abusedopamine receptor partial agonist
magnesium sulphateeclampsiaintravenous fluid[Late pregnancy complications], [Acute presentation of diabetes mellitus], [Infectious disease outbreak], [Postoperative care], [Postoperative complications]
MDMA (3,4-methylenedioxy-N-methylamphetamine, ectasy)drugs of abuseamphetamine like sympathomimetic
medroxy progesterone acetatemenopause, heavy menstrual bleedingprogesterone receptor agonistlevonorgestrel, desogestrel
meropenembacterial infectionbeta-lactamase resistant beta-lactam cell wall damage (Class: antibacterial: beta-lactam - carbapenem)
mesalazineinflammatory bowel diseasesalicylate like anti-inflammatory
metformintype 2 diabetesinsulin sensitizer[Amenorrhea], [Diabetes in pregnancy], [Infertility], [Obesity], [Type 2 diabetes mellitus]
methotrexatecancer, autoimmune diseaseinhibition of dihydrofolate reductase, inhibition of purine metabolism, inhibition of T lymphocyte activity (Class: immunosuppressant)[Gynaecological abdominal pain], [Itching child], [Rash on extensor surfaces and joint pains]
methyldopahypertensionalpha-2 adrenoceptor agonist (prodrug)[Risk assessment in early pregnancy]
metoclopramidenausea and vomitingdopamine (D2) receptor antagonist[Bowel obstruction], [Chronic bowel motility problems], [Chronic upper abdominal symptoms], [Head trauma], [Penetrating chest trauma], [Preoperative assessment and management], [Sudden onset severe headache]
metoprololhypertension, ischaemic heart disease, arrhythmias, congestive heart failurebeta-1 adrenoceptor antagonistbisoprolol, carvedilol
metronidazolebacterial infectioncysteine bearing enzyme inhibitor (prodrug) (Class: antibacterial: nitroimidazole)[Acute abdominal pain], [Chronic limb pain], [Diarrhoea], [Perianal pathology], [Postoperative complications]
mifepristonetermination of pregnancyprogesterone receptor agonist, g;ucocorticoid receptor antagonist
misoprostolmiscarriage (preoperative)prostaglandin E1 analogue[Gynaecological abdominal pain]
montelukastasthma, chronic obstructive pulmonary diseaseleukotriene receptor antagonist[Child with respiratory distress], [Sudden onset shortness of breath]
morphinepain, drugs of abusemu-opioid receptor agonist
N-acetylcysteineparacetamol overdoseglutathione precursor (prodrug)[Overdose in a child or adolescent]
naloxoneopioid overdosemu-opioid receptor antagonist[Preoperative assessment and management]
nifedipinehypertension, angina, tocolysis for preterm labourcalcium channel blocker (Class: dihydropyridine)amlodipine[Late pregnancy complications]
norethisteronemenopause, contraceptionprogesterone receptor agonistlevonorgestrel, desogestrel[Contraception]
nortriptylinedepression, painneuroamine transmitter uptake inhibitor (Class: antidepressant: tricyclic)amitriptyline
oestradiol valeratemenopause, osteoporosisoestrogen analogueconjugated equine oestrogen, oestradiol
olanzapinepsychosismixed dopamine, serotonin, muscarinic receptor antagonist[Acute psychosis], [Agitated and combative patient], [Delirium / dementia]
omeprazolepeptic ulcer diseaseproton pump inhibitor[Chronic upper abdominal symptoms], [Painful hands in the cold]
ondansetronnausea and vomitingserotonin (5HT3) antagonist[Acute abdominal pain], [Bowel obstruction], [Head trauma], [Penetrating chest trauma], [Preoperative assessment and management], [Sudden onset severe headache]
oxycodonepainmu-opioid receptor agonist
oxygenhypoxiaoxygenation[Anaemia], [Chronic shortness of breath], [Infant or child with a murmur], [Neonatal stridor], [Labour]
oxytocininduction or augmentation of labour, post partum haemorrhageoxytocin receptor agonist
paclitaxelcancerstabilises microtubules (Class: chemotherapy)
paracetamolpain, inflammationcyclooxygenase inhibitor and cannabinoid modulator[Accidental overdose], [Acute abdominal pain], [Acute abdominal pain in children and adolescents], [Child or adolescent with a headache], [Dislocated joint], [Head trauma], [Inflammatory low back pain], [Overdose in a child or adolescent], [Postoperative care], [Postoperative complications], [Preoperative assessment and management], [Self-harm], [Superficial injuries]
permethrinscabiessodium channel opener[Rest home resident with itching and rash]
pethidinepainmu-opioid receptor agonist[Dislocated joint]
phenelzinedepressionmonoamine oxidase A inhibitor
phenobarbitalepilepsyGABA-A receptor sensitizer and agonist[Unexplained loss of consciousness]
phenytoinepilepsysodium channel blocker[Altered level of consciousness in a child], [Chronic illness in paediatrics], [Unexplained loss of consciousness]
pioglitazonetype 2 diabetesperoxisome proliferator-activated receptor gamma agonist
pramipexoleParkinson's diseasedopamine receptor agonist
prednisoneinflammatory disease, steroid deficiencyanti-inflammatory corticosteroidmethylprednisolone[Adrenal crisis], [Chronic shortness of breath], [Adult eczema], [Headache, morning stiffness and shoulder pain], [Hip fracture], [Itching child], [Sudden loss of vision and headache], [Sudden onset shortness of breath]
probenecidgoutorganic anion transporter antagonist
prochlorperazinenausea and vomitingdopamine receptor antagonist
procyclidineParkinson's diseasemuscarinic cholinergic receptor antagonist
propofolanaesthesiaGABA-A receptor sensitizer and sodium channel blocker[Preoperative assessment and management]
propranololhypertension, anxietybeta-1 adrenoceptor antagonist
protamine sulfateheparin reversalbinds heparin to form stable ion pair without anticoagulant activity
pyridoxinepyridoxine deficiency, sideroblastic anaemiavitamin B6 replacement
quetiapinepsychosisdopamine,serotonin, histamine (H1) and alpha-adrenergic antagonist[Acute psychosis], [Delirium / dementia]
raloxifeneosteoporosisselective estrogen receptor modulator
raltegravirHIV infectionintegrase inhibitor (Class: antiviral)
ranibizumabwet age-related macular degenerationvascular endothelial growth factor inhibitor[Gradual deterioration in visual acuity over time]
ranitidinepeptic ulcer diseasehistamine (H2) receptor antagonist
rasagilineParkinson's diseasemono-amine-oxidase B inhibitor
ribavirinBroad spectrum against RNA virus including HCVRNA nucleotide analogue (Class: antiviral)
rifampicintuberculosisbacterial DNA-dependent RNA polymerase inhibitor (Class: antibacterial)[Haemoptysis and abnormal chest X-ray]
risperidonepsychosisdopamine, serotonin, histamine (H1) and adrenergic antagonist[Acute psychosis], [Delirium / dementia]
rituximabrheumatoid arthritis, B cell lymphoma/leukaemiaCD20 B cell killer (Class: monoclonal antibody)[Lymphadenopathy and splenomegaly]
ropiniroleParkinson's diseasedopaminergic agonist
salbutamolasthma, chronic obstructive pulmonary diseasebeta-2 adrenoceptor agonist[Child with respiratory distress], [Chronic shortness of breath], [Sudden onset shortness of breath]
salmeterolasthma, chronic obstructive pulmonary diseasebeta-2 adrenoceptor agonist[Child with respiratory distress], [Chronic shortness of breath], [Sudden onset shortness of breath]
scopolaminemotion sicknessmuscarinic cholinergic receptor antagonist[Bowel obstruction], [Penetrating chest trauma], [Sudden onset severe headache]
selegilineParkinson's diseasemono-amine-oxidase B inhibitor
sennoside Bconstipation (irritable bowel syndrome)intestinal nerve plexus stimulant
simvastatindyslipidemiaHMG-CoA reductase inhibitor
sitagliptintype 2 diabetesdipeptidyl peptidase-4 inhibitor
sodium valproateepilepsyGABA neurotransmission sensitizer[Bipolar affective disorder], [Unexplained loss of consciousness]
sotalolarrhythmiasbeta-adrenoceptor antagonist and potassium channel blocker[Arrhythmias]
spironolactonehypertension, heart failurealdosterone antagonist[Heart failure], [Secondary hypertension]
streptokinasemyocardial infarction, cerebrovascular accident (stroke)plasminogen activator[Acute chest pain]
sulphamethoxazole/trimethoprimbacterial infectiondihydrofolate reductase inhibitor & dihydropteroate synthetase inhibitor (Class: antibacterial: sulfonamide)trimethoprim
sulphasalazineinflammatory arthritisintestinal inflammation modulator
sumatriptanmigraineserotonin (5HT1) receptor agonist
suxamethoniumanaesthesianicotinic cholinergic receptor agonist
tamoxifenbreast cancermixed oestrogen receptor agonist/antagonist
temazepamsedationbenzodiazepine receptor agonist
tenofovirHIV/HBV infectionnucleoside reverse transcriptase inhibitor (Class: antiviral)
terbinafinefungal infectionergosterol synthesis inhibitor (Class: antifungal)[Rest home resident with itching and rash]
testosteronehypogonadismtestosterone receptor agonist[Obesity], [Panhypopituitarism]
theophyllineasthma, chronic obstructive pulmonary diseaseadenosine receptor antagonist and phosphodiesterase inhibitor
thiaminethiamine deficiency,Wernicke’s encephalopathyvitamin B1 replacement[Alcohol and drug dependence disorders]
thiopental sodiumanaesthesiaGABA-A receptor sensitizer
thioridazinepsychosisdopamine receptor antagonist
tiotropiumasthma, chronic obstructive pulmonary diseasemuscarinic cholinergic receptor antagonist[Chronic shortness of breath]
tissue plasminogen activator(recombinant)thrombolytic therapy of ischaemic stroke, myocardial infarction, massive pulmonary embolismcatalysis of plasminogen to plasmin
tramadolpainmu-receptor opioid partial agonist (prodrug)[Dislocated joint]
tranexamic acidprevention and treatment of excessive bleeding (menorrhagia, surgery, coagulation/platelet disorders)antifibrinolytic[Heavy menstrual periods]
tranylcyprominedepressionmono-amine-oxidase A inhibitor
trastuzumabbreast cancerHER2/neureceptor antagonist (Class: monoclonal antibody)
ustekinumabpsoriasisinterleukin (12 and 23) inhibitor
vancomycinbacterial infectionscell wall damage - interferes with transpeptidation between peptidoglycan subunits[Chronic limb pain], [Fever and a new murmur], [Pre-admission and surgical risk assessment]
vecuroniumanaesthesianicotinic cholinergic receptor antagonist
venlafaxinedepressionserotonin-noradrenaline reuptake inhibitor (SNRI)
verapamilhypertension, arrhythmiascalcium channel blocker (Class: phenylalkylamine)
vinblastinecancerdisrupts microtubule assembly (Class: chemotherapy)
vitamin K1prophylaxis/treatment haemorrhagic disease of the newborn, warfarin reversal, vitamin K deficiencycofactor for gamma-glutamyl carboxylase (catalyses carboxylation of glutamic acid residues on vitamin K-dependent proteins)
warfarinvenous thromboembolism, valvular disease, atrial fibrillationvitamin K epoxide reductase inhibitorrivaroxaban[Accidental overdose], [Acutely painful limb], [Arrhythmias], [Deep vein thrombosis], [Epistaxis], [Fever and a new murmur], [Unexplained loss of consciousness]
zoledronateosteoporosisosteoclast inhibitor (Class: bisphosphonate)
zopiclonesedationbenzodiazepine receptor agonist[Self-harm]
MedicineYr6Indication(s)MechanismOther Example(s)Relevant Scenario(s)