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Diabetes insipidus

Clinical Discipline(s)/Organ System(s)
Endocrinology, Renal Medicine
Progress Test Topic(s)
Homeostasis
Description
You are on your GP placement and are asked to see a 19 year old NZ European woman who has been drinking lots of water for the past couple of months. She can't go anywhere without a bottle of water. She says she does this because she is always going to the toilet and gets up 3-4 times each night to drink. She has normal body weight.
Progress Test-Type Questions:   Question 1 | Question 2
Applied Science for Medicine 
   - Anatomy of the hypothalamus and pituitary gland
   - Controls of antidiuretic hormone (ADH; also known as vasopressin) release
   - End-organ effects of ADH
   - Renal mechanism for concentrating urine
   - Mechanisms that promote thirst
   - Pharmacology of desmopressin
Clinical and Communication Skills 
   - Elicit a history from a polydipsic, polyuric patient; consider family history, past head trauma, past meningitis and intracranial surgery
   - Examine the polydipsic, polyuric patient; assess fluid balance and visual fields
   - Interpret serum and urine osmolality, urine dipstick
   - Differential diagnosis of polyuric patient
   - Differential diagnosis of abnormalities in serum sodium
   - Indications for water deprivation test
   - Define diabetes insipidus and explain the two types
   - Drugs that cause diabetes insipidus
   - Complications of diabetes insipidus
   - Management of central and nephrogenic diabetes insipidus
Personal and Professional Skills 
   - Knowing when to refer to specialist
Population Health 
   - Epidemiology of diabetes insipidus
Conditions to be considered relating to this scenario
Common
central diabetes insipidus, nephrogenic diabetes insipidus, primary polydipsia, diabetes mellitus, urinary tract infection, hypokalaemia
Uncommon
medullary sponge kidney