Applied Science for Medicine Biochemistry, physiology and pharmacology of paracetamol and iron supplements when taken in overdose Drug absorption, metabolism and excretion Drug dosing and calculations Genetic polymorphisms that alter individual responses to drugs Prescribing for children Clinical toxicology in the paediatric population
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Clinical and Communication Skills Understand the principles of triage with children presenting with poisoning Basic resuscitation if depressed level of consciousness Elicit history of ingestion (time, amount, calculate maximum quantity), and consider multiple drug ingestion Signs and symptoms suggesting toxicity such as cholinergic: (organophosphates) salivation, sweating, bronchospasm or anticholinergic: dry flushed skin, mydriasis, seizures, ECG changes Manage poisoning (e.g. paracetamol) overdose including first aid, blood and urine toxicology assessment, interpretation of levels, identify relevant end organs that may be affected, use of antidotes (use of paracetamol nomogram and N-acetylcysteine) Calculate appropriate drug doses for individual patients by weight and body surface area Access the New Zealand National Poisons Centre website for advice Assessment of household risks and safety in case of younger children Understanding of interventions; role child proof lids, home medicines safety Assessment of adolescent in case of intentional overdose (HEADSS assessment and full psychiatric evaluation) Management of deliberate self harm/suicidal behaviour in children and adolescents
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